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  • Jinan Xinzheng Pharmaceutical Technology Co., Ltd
  • Tel:18615218958
  • Phone:18668900978
  • Fax:+86-531-88798968
  • E-Mail:xinzhengpharm@163.com
  • Address:Room 0416, Tower B, Building No 1, Jinan pharm valley, Hi-tech District, Jinan, Shandong, China
Product

4-Chloro-N-methylpyridine-2-carboxamide

CAS No:220000-87-3     
Usages:intermediate of sorafenib and regorafenib
Introduction:
 

项目

Item

质量标准

Standard

外观

Appearance

白色至淡黄色固体或液体

White to pale yellow solid or liquid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(GC)

Purity

>99.00%

关键杂质(GC)

Critical Impurity

<0.5%

单一杂质(GC)

Single Impurity

<0.3%

重金属

Heavy Metals

<20ppm

水分

Water

<0.50%

包装规格:1 kg,5 kg或10kg氟化瓶

Packing: 1 kg, 5 kg or 10kg net in fluorinated bottle

 

4-Chloro-3-(trifluoromethyl)-benzenamine

CAS No:320-51-4     
Usages:intermediate of sorafenib and regorafenib
Introduction:
 

项目

Item

质量标准

Standard

外观

Appearance

类白色固体或淡黄色液体

Off-white solid or light brown liquid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(GC)

Purity

>99.00%

包装规格:1 kg,5 kg或者10kg

Packing: 1 kg or 5 kg or 10kg

 

4-Chloro-3-trifluoro-m-tolyl isocyanate

CAS No:327-78-6     
Usages:intermediate of sorafenib and regorafenib
Introduction:

 

项目

Item

质量标准

Standard

外观

Appearance

白色至淡黄色固体或液体

White to pale yellow solid or liquid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(GC)

Purity

>99.00%

关键杂质(GC)

Critical Impurity

<0.5%

单一杂质(GC)

Single Impurity

<0.3%

重金属

Heavy Metals

<20ppm

包装规格:1 kg,5 kg或10kg氟化瓶

Packing: 1 kg, 5 kg or 10kg net in fluorinated bottle

 

Sorafinib mesylate

CAS No:475207-59-1     
Usages:sorafenib
Introduction:
 

项目

Item

质量标准

Standard

外观

Appearance

类白色至黄色固体粉末

Off white to yellow solid powder

鉴别

Identification

供试品溶液保留时间应与对照品溶液一致

The retention time of principal peaks of the test solution is identical with that of the standard solution

纯度(HPLC)

Purity

>99.00%

总杂质(HPLC)

Total Impurity

<0.5%

单一杂质(HPLC)

Single Impurity

<0.3%

重金属

Heavy Metals

<20ppm

水分

Water

<0.50%

包装规格:1 kg,5 kg或10kg

Packing: 1 kg, 5 kg or 10kg

 

4-Amino-3-fluorophenol

CAS No:399-95-1     
Usages:intermediate of regorafenib
Introduction:

 

项目

Item

质量标准

Standard

外观

Appearance

棕褐色固体

Dark brown solid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(HPLC)

Purity

>97.00%

对氨基苯酚(HPLC)

4-Aminophenol

<0.1%

重金属

Heavy Metals

<20ppm

水分

Water

<0.50%

包装规格:1 kg,5 kg或10kg

Packing: 1 kg, 5 kg or 10kg

4-Amino-3-chlorophenol

CAS No:17609-80-2     
Usages:intermediate of lenvatinib
Introduction:

 

项目

Item

质量标准

Standard

外观

Appearance

棕褐色固体

Dark brown solid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(HPLC)

Purity

>98.00%

对氨基苯酚(HPLC)

4-Aminophenol

<0.1%

重金属

Heavy Metals

<20ppm

水分

Water

<1.0%

包装规格:1 kg,5 kg或10kg

Packing: 1 kg, 5 kg or 10kg

4-(4-Aminophenoxy)-N-methylpicolinamide

CAS No:284462-37-9     
Usages:intermediate of sorafenib
Introduction:
 

项目

Item

质量标准

Standard

外观

Appearance

类白色固体至棕黄色固体

Off-white solid to brown liquid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(HPLC)

Purity

>99.00%

单一杂质(HPLC)

Single Impurity

<0.5%

重金属

Heavy Metals

<20ppm

水分

Water

<0.50%

包装规格:1 kg,5 kg或10kg

Packing: 1 kg, 5 kg or 10kg

 

4-Chloropyridine-2-carboxamide

CAS No:99586-65-9     
Usages:for study on the impurities of sorafenib and regorafenib
Introduction:
 

项目

Item

质量标准

Standard

外观

Appearance

白色至淡黄色固体

White to pale yellow solid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(GC)

Purity

>99.00%

关键杂质(GC)

Critical Impurity

<0.5%

单一杂质(GC)

Single Impurity

<0.3%

重金属

Heavy Metals

<20ppm

水分

Water

<0.50%

包装规格:1 kg,5 kg或10kg

Packing: 1 kg, 5 kg or 10kg

 

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

CAS No:757251-39-1     
Usages:intermediate of regorafenib
Introduction:
 

项目

Item

质量标准

Standard

外观

Appearance

类白色固体至棕黄色固体

Off-white solid to brown liquid

鉴别

Identification

供试品溶液所显主斑点的Rf应与对照品溶液的主斑点一致

TLC shows the Rf of the test solution corresponds to that of the standard solution

纯度(HPLC)

Purity

>90.00%

重金属

Heavy Metals

<20ppm

水分

Water

<0.50%

包装规格:1 kg,5 kg或10kg

Packing: 1 kg, 5 kg or 10kg

 

Regorafenib

CAS No:755037-03-7     
Usages:regorafenib
Introduction:
 

项目

Item

质量标准

Standard

外观

Appearance

类白色至黄色固体粉末

Off white to yellow solid powder

鉴别

Identification

供试品溶液保留时间应与对照品溶液一致

The retention time of principal peaks of the test solution is identical with that of the standard solution

纯度(HPLC)

Purity

>99.00%

总杂质(HPLC)

Total Impurity

<0.5%

单一杂质(HPLC)

Single Impurity

<0.1%

重金属

Heavy Metals

<20ppm

水分

Water

<0.50%

包装规格:1 kg,5 kg或10kg

Packing: 1 kg, 5 kg or 10kg